Air trapping is a major determinant of persistent airway obstruction in asthmatics
نویسندگان
چکیده
منابع مشابه
Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway inflammation.
BACKGROUND Airway hyperresponsiveness is the ability of airways to narrow excessively in response to inhaled stimuli and is a key feature of asthma. Airway inflammation and ventilation heterogeneity have been separately shown to be associated with airway hyperresponsiveness. A study was undertaken to establish whether ventilation heterogeneity is associated with airway hyperresponsiveness indep...
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STUDY OBJECTIVES To characterize the relationship between symptoms and the degree of airway obstruction as determined by the FEV1 and peak expiratory flow (PEF) in a cohort of adult patients attending a university-based urban asthma clinic. DESIGN Each of six current asthma symptoms, including cough, dyspnea, wheeze, chest tightness, sputum production, and nocturnal awakening was rated by pat...
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INTRODUCTION Our knowledge about atopy as a longitudinal predictor of asthma is limited. The purpose of this study was to investigate the prognosis of asthma and risk factors for asthma onset, especially sensitization of specific allergens in a population sample. MATERIAL AND METHODS A cohort responded to a respiratory questionnaire in 1990 and 2003. At baseline, 2,060 subjects who, in the sc...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2012
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2012.02.012